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Why don't red blood cells have nuclei?

Answer

Red blood cells are the only cells in the human body that don't have a nucleus. This is an adaptation which allows the red blood cell to carry more oxygen, but the down side is that the cell cannot replicate itself. The iron in the body is used to make new red cells, which is why iron is such an important part of a person's diet.
1 Additional Answer
Because they don't need one. The nucleus of a cell is responsible for cellular activity including cell division. Blood cells don't divide, they are produced by other cells within bone marrow. RBC's are mainly a cell membrane surrounding a glob of hemoglobin and they lack most of the organelles associated with living cells.
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